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Symptoms of Fluoroquinolone Antibiotic Toxicity Syndrome

 

SYMPTOMS:
 
Musculoskeletal:
Tendon pain
Tendon rupture
Joint pain
Popping/cracking joints
Muscle pain
Muscle weakness
Muscle wasting Muscle wasting or muscle atrophy
Muscle tightness/contractures
Back pain
Exercise intolerance
Loss of padding on palms or bottoms of feet
Accelerated disc degeneration
Inflammation of the rib junctions to sternum [Costochondritis]
 
PNS:
Tingling, prickling, pins&needles, or numbness, bugs running on skin, water trickling, fabric moving, in arms or legs
Buzzing, in arms or legs
Pressure or squeezing feelings, in arms or legs
Feelings of electrical zaps, shocks, or deep stabs, in arms or legs
Burning pain in arms or legs (this can also be tendinopathy, but mark here anyway)
Pain with normally non-painful touch or hypersensitivity to pain (allodynia, hyperalgesia)
Teeth, mouth, and lip nerve pain, of any kind (shocks, tingling, buzzing, etc.)
Facial nerve pain of any kind (Trigeminal neuralgia)
Squeezing feelings on head, "Head pressure" feelings
Muscle twitching of small pieces of a muscle independently [Fasciculations]
Muscle twitching of whole muscle body (Tremors)
Neuralgia (pain along nerve trunk lines)
 
CNS:
Insomnia
Panic/Anxiety
Brain Fog (impaired thinking)
Memory loss (including impaired short term memory)
Aphasia
Confusion
Abnormal dreams
Headaches
Depersonalization
Depression
Thoughts of suicide
Agitation / personality changes
Hallucinations
Seizures
 
Dermatological:
Itching [Pruritis]
Dry skin and dry patches
Hair loss [Alopecia]
Loss of collagen in skin; sudden development of extensive wrinkles on face, hands
Raised ridges down fingernails
Skin rash
Poor wound healing; reopening scars or cuts or (internal) surgery sites or meniscus tear
Easy Sunburn [Phototoxicity]
 
Gastrointestinal:
Difficulty swallowing [dysphagia]
Abdominal pain
Persistent Softer stool lasting more than 2 weeks
Persistent Diarrhea lasting more than 2 weeks
Persistent Constipation lasting more than 2 weeks
Delayed gastric emptying
Chronic nausea lasting more than 2 weeks
Acid reflux lasting more than 2 weeks
Bloating / Gas / Abdominal distension
Undigested food in stool
Foul / unusual smelling stool
Persistent oral candidiasis (aka “thrush”)
Food sensitivities
Inability to digest food [Maldigestion]
 
Vision:
Eye focusing problems
Dry eyes
Light sensitivity [Photophobia]
Floaters
Visual acuity decrease
Double vision [Diplopia]
Black specks
Drooping eyelids [Ptosis]
Retinal tears
Inability to process all visual input (still verifying this one)?
 
Ear Nose Throat:
Ringing in ears [Tinnitus]
Dizziness (vertigo)
Lack of sense of balance, feels like being on rolling boat [No Equilibrioception]
Hearing sensitivity to low noises increased [Hyperacusis]
Hearing loss
Ear wax reduced or replaced by dry grit
Dry mouth
Taste perversions [Dysgeusia]
Smell of odors increased [Hyperosmia]
Smell things not there [Phantosmia]
Difficulty speaking, producing vocal sound [Dysphonia]
 
Cardiovascular:
Heart Palpitations
Poor peripheral vascular circulation (cold feet/hands)
Heart rate at rest above 100 beats per minute [Tachycardia]
Swelling limbs [Edema]
Purple or red spots under skin esp. in limbs [Purpura, Petechiae]
Easy / excessively large bruising
Swollen veins
Sudden change in hand color, with severe coldness and numbness lasting a few minutes [Raynaud's phenomenon]
Low blood pressure, including Postural Orthostatic Hypotension (POTS) [Hypotension]
High blood pressure [Hypertension]
Shortness of breath
 
Autonomic Nervous System (Dysautomia):
Lightheadedness
Sweating inappropriately much for environment [Hyperhidrosis]
Lack of sweating, even in hot environments [Anhidrosis]
Pupils don’t dilate appropriately for night/day lighting [Pupillary dysfunction]
 
Endocrine:
Feeling cold consistently
Unexplained weight change (usually loss)
New thyroid abnormalities
Hypoglycemia
Diabetes [Hyperglycemia]
New endocrine abnormality other than above
 
Urinary System:
Excessive thirst and urination [Polydipsia, Polyuria]
Rhabdomyolysis
Purple, brown, red, or frothy urine [renal pathology]
 
Reproductive:
Loss of male libido [Male hypogonadism]
Loss of nighttime / morning erections [Male hypogonadism]
Low testosterone [male hypogonadism]
Reduced ejaculate
Testicular pain
Penile Tissue Changes (narrowing, shrinkage, wrinkled)
Ovarian cysts
Missing menstruation 3 months or more [Amenorrhoea]
Dry vagina during Intercourse
Heavier/longer menstrual bleeding
 
Dental:
Softer oral gum tissue or abnormally bleeding gums
Broken teeth
Many new cavities
Tooth pain
Other new dental problems
 
Constitutional/General:
Fatigue
Multiple Chemical Sensitivity
 
 
Pyschological and Social:
Discounting of your symptoms by doctors
Mocking of your symptoms by doctors
Dislike of medication use
Fear of doctor appointments
Discounting of my symptoms by friends
Discounting of my symptoms by family
 
 
Exacerbation Triggers:
Stress
Lack of sleep
Exercise beyond personal physical limitations
Weather related storms and temperature changes
Anxiety
Illness
Seasons
Electrical Sensitivity (e.g. to MRI procedure)
Cold Weather
 
 
Hormonal Exacerbation Triggers:
Ovulation
Secretory/Luteal menstrual phase (between ovulation and menstruation)
Impending menstruation
...Possibly post-orgasm for males
 
 
Food Sensitivities:
Caffeine
Sugar
Alcohol
MSG
Soy
Gluten
Dairy
Nightshades (tomatoes, white potatoes, , eggplant, peppers)
Acidic foods (e.g. vinegar, tomatoes, lemon juice, lime juice)
Sulfites
Aspartame
Carbonated beverages (non-alcoholic)
Corn
 
 
Specific Animal Product Exacerbation Triggers:
Beef
Poultry
Fish (non-shellfish)
Shellfish (shrimp, scallops, crab, lobster, clams)
Pork
Lamb
Other red meat

 


 

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FATSN - 2014